This study aimed to identify and analyze the dimensions affecting the livability of multifunctional urban centers and determine their effects on user satisfaction in Tehran. The applied research employed a descriptive survey design, using structural equation modeling (SEM) to examine relationships among the study variables. The statistical population comprised users of multifunctional urban centers in Tehran. Data were collected using a standardized questionnaire based on a five-point Likert scale. Six dimensions of livability were examined: physical, social, economic, cultural, environmental, and transportation. Confirmatory factor analysis supported the validity and reliability of the research instrument, while model fit indices indicated acceptable measurement and structural models. The findings showed that all six dimensions had positive and statistically significant effects on user satisfaction. The physical dimension had the strongest effect (path coefficient = 0.412), followed by transportation (0.388), social (0.351), cultural (0.302), economic (0.269), and environmental (0.214) dimensions. Collectively, the study variables explained more than 71% of the variance in user satisfaction. These findings suggest that improving environmental design quality, enhancing transportation accessibility, strengthening social interactions, expanding cultural activities, and prioritizing environmental sustainability are important strategies for improving livability and user satisfaction in Tehran’s multifunctional urban centers. The results also underscore the importance of integrated planning approaches that consider both the functional characteristics of these centers and users’ experiences when establishing priorities for urban development and management within the broader context of increasingly complex metropolitan environments.